Cytokeratin on frozen sections of sentinel node may spare breast cancer patients secondary axillary surgery.

Conclusions. IHC on frozen section leads to the detection of more ITC and MIC intraoperatively. As axillary lymph node dissection (ALND) is performed routinely in some countries when ITC and MIC are found in the SN, IHC on frozen section provides valuable information that can lead to fewer secondary ALNDs. PMID: 22655220 [PubMed]
Source: Pathology Research International - Category: Pathology Tags: Patholog Res Int Source Type: research