ATG9 raises the BAR for PI4P in autophagy

ATG9 vesicles are crucial for autophagy, yet the role of ATG9 remains unclear. In this issue, Judith et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201901115) implicate the BAR protein Arfaptin2 in the loading of PI4-kinase IIIβ onto ATG9 vesicles for recruitment of ATG13 to the site of autophagosome biogenesis.

Source: Journal of Cell Biology - May 5, 2019 Category: Cytology Authors: Shatz, O., Elazar, Z. Tags: Spotlight Source Type: research