Quantification of active pharmaceutical ingredient and impurities in sildenafil citrate obtained from the Internet

Conclusions: Quality assurance tests are often used to detect formulation defects of drug products during the manufacturing and/or storage process. Results suggest that manufacturing standards for sildenafil citrate generic drug products compared with the US innovator product are not equivalent with regards to potency and levels of impurities. These findings have implications for safety and effectiveness that should be addressed by clinicians to safeguard consumers who choose to purchase sildenafil citrate and foreign-manufactured drugs, in general, via the Internet.
Source: Therapeutic Advances in Drug Safety - Category: Drugs & Pharmacology Authors: Tags: Original Research Source Type: research