Adrenal cortical adenoma with the maximal diameter greater than 5 cm: can they be differentiated from adrenal cortical carcinoma by CT?

Adrenal cortical adenoma with the maximal diameter greater than 5 cm: can they be differentiated from adrenal cortical carcinoma by CT? Int J Clin Exp Med. 2014;7(10):3136-3143 Authors: Tian L, Dong J, Mo YX, Cui CY, Fan W Abstract To study the computed tomographic findings of adrenal adenoma with the maximal diameter greater than 5 cm and to discuss whether such tumor can be differentiated from adrenal carcinoma by CT examination. Fourteen consecutive patients with adrenal adenoma with the maximal diameter larger than 5 cm, proven pathologically, were enrolled. All patients underwent non-enhanced and contrast-enhanced CT examination. The CT findings, including size, shape, edge, density on non-enhanced CT and schedule of reinforcement after contrast administration for each lesion were retrospectively analyzed. CT data of 13 patients with adrenocortical carcinoma were also evaluated to determine whether differentiating characteristics existed. The maximal diameter of the 14 masses of adenoma ranged from 5.5 cm to 20 cm (mean, 10 cm). One mass showed lobulated, the rest 13 masses showed rounded or ovoid. Eleven and 3 masses appeared well-circumscribed and ill-circumscribed, respectively. All of 14 masses presented heterogeneous density on non-enhanced CT images with patchy low-attenuation foci or stippled calcification. All of 14 masses revealed moderately to markedly heterogeneous enhancement after contrast administration. None of 14...
Source: International Journal of Clinical and Experimental Medicine - Category: Drugs & Pharmacology Tags: Int J Clin Exp Med Source Type: research