The COP1 E3-ligase interacts with FIP200, a key regulator of mammalian autophagy

Conclusions:
These data suggest that COP1 modulates FIP200-associated activities, which may contribute to a variety of cellular functions that COP1 is involved in.

Source: BMC Biochemistry - January 6, 2013 Category: Biochemistry Authors: Saori KobayashiNoriko Yoneda-KatoNagisa ItaharaAkihiro YoshidaJun-ya Kato Source Type: research