The effect of ascorbic acid and fluid flow stimulation on the mechanical properties of a tissue engineered pelvic floor repair material

In conclusion, a pelvic floor repair material with improved mechanical properties can be developed by supplementing culture media with ascorbic acid-2-phosphate to increase collagen I production. Future studies will assess the change in mechanical properties after implantation in an animal model.

Source: Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine - October 13, 2014 Category: Biomedical Engineering Authors: Osman, N. I., Roman, S., Bullock, A. J., Chapple, C. R., MacNeil, S. Tags: Original Articles Source Type: research