Recombinant human growth hormone for treating burns and donor sites

Source: Cochrane Area: Evidence > Drug Specific Reviews   Background   Recombinant human growth hormone (rhGH) increases protein synthesis, therefore it is used in burns with a total body surface area (TBSA) greater than 40%, where there is frequently an increase in protein breakdown and a decrease in protein synthesis. This change in protein metabolism correlates with poor wound healing of the burn and donor sites.     Objectives   To determine the effects of rhGH on the healing rate of burn wounds and donor sites in people with burns.         Search methods   We searched the Cochrane Wounds Group Specialised Register (searched 28 June 2012); The Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2012, Issue 6); Database of Abstracts of Reviews of Effects (DARE) (The Cochrane Library 2011, Issue 3); Ovid MEDLINE (1950 to June Week 3 2012); Ovid MEDLINE (In-Process & Other ...
Source: NeLM - Drug Specific Reviews - Category: Drugs & Pharmacology Source Type: news