Lipid lowering efficacy of atorvastatin

Source: Cochrane Area: Evidence > Drug Specific Reviews Background   Atorvastatin is one of the most widely prescribed drugs and the most widely prescribed statin in the world. It is therefore important to know the dose-related magnitude of effect of atorvastatin on blood lipids.       Objectives     To quantify the dose-related effects of atorvastatin on blood lipids and withdrawals due to adverse effects (WDAE). Search methods We searched the Cochrane Central Register of Controlled Trials (CENTRAL) on The Cochrane Library Issue 4, 2011, MEDLINE (1966 to November 2011), EMBASE (1980 to November 2011), ISI Web of Science (1899 to November 2011) and BIOSIS Previews (1969 to November 2011). No language restrictions were applied.       Selection criteria     Randomised controlled and uncontrolled before-and-after trials evaluating the dose response of different fixed doses of atorvastatin on blood lipids over ...
Source: NeLM - Cardiovascular Medicine - Category: Cardiology Source Type: news