SSRIs during pregnancy and risk of stillbirth and infant mortality

Source: JAMA Area: News This population-based cohort study evaluated the risk of stillbirth and infant mortality associated with use of SSRIs during pregnancy.   Participants were from all Nordic countries (Denmark, Finland, Iceland, Norway, and Sweden) at different periods from 1996 to 2007 and included women with singleton births. Information on maternal use of SSRIs was obtained from prescription registries and that relating to maternal characteristics, pregnancy, and neonatal outcomes, from patient and medical birth registries.   The following findings were reported:   . Among 1,633,877 singleton births in the study, 6054 were stillbirths; 3609, neonatal deaths; and 1578, postneonatal deaths.   . 29,228 (1.79%) of mothers had filled a prescription for an SSRI during pregnancy.   . Women exposed to an SSRI presented with higher rates of stillbirth (4.62 vs. 3.69 per 1000, p=0.01) and postneonatal death (1.38 vs. 0.96 per 1000, ...
Source: NeLM - Mental Health - Category: Psychiatry Source Type: news