Recovery of the failing heart: emerging approaches and mechanisms in excitation-contraction coupling.

Recovery of the failing heart: emerging approaches and mechanisms in excitation-contraction coupling. F1000Prime Rep. 2014;6:27 Authors: Ibrahim M, Edlin JC, Nader A, Terracciano CM Abstract Heart failure (HF) is a growing cause of morbidity and mortality globally. All clinical therapies that reduce mortality have been shown to induce reverse remodeling. In this article, we discuss a conceptual approach to the evolving treatment of HF using emerging treatment modalities for the drug-refractory patient. This approach is based on the combinatorial, integrated application of therapies shown to influence reverse remodeling in the laboratory. PMID: 24904750 [PubMed]
Source: F1000 Medicine Reports - Category: Biomedical Science Tags: F1000Prime Rep Source Type: research