Microbiome analysis - from technical advances to biological relevance.

Microbiome analysis - from technical advances to biological relevance. F1000Prime Rep. 2014;6:51 Authors: Smith MI, Turpin W, Tyler AD, Silverberg MS, Croitoru K Abstract The development of culture-independent techniques and next-generation sequencing has led to a staggering rise in the number of microbiome studies over the last decade. Although it remains important to identify the taxa of microbes present in a variety of environmental samples, including the gut microbiomes of healthy and diseased individuals, the next stage of microbiome research will need to focus on uncovering the role of the microbiome rather than its mere composition. Here, we introduce techniques that go beyond identifying the taxa present within a sample and examine the biological function of the microbiome or the host-microbiome interaction. PMID: 25184041 [PubMed]
Source: F1000 Medicine Reports - Category: Biomedical Science Tags: F1000Prime Rep Source Type: research