Beta-Defensin 124 Is Required for Efficient Innate Immune Responses in Prostate Epithelial RWPE-1 Cells.
CONCLUSIONS: Taken together, these results provide strong evidence for the first time that increased DEFB124 expression via NF-κB activation in PGN-exposed RWPE-1 cells enhances the production of cytokines and chemokines, which may contribute to an efficient innate immune defense.
PMID: 24955228 [PubMed]
Source: Korean Journal of Urology - Category: Urology & Nephrology Tags: Korean J Urol Source Type: research
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