Effectiveness of the Typhoid Vi Vaccine in Overseas Travelers from England

ConclusionsThe vaccine has been demonstrated to have a similar effectiveness in travelers as that found in endemic populations. It appears to be protective in all ages, including in young children (aged 2–5 years), a finding not consistently replicated in other studies. However, good hygiene practices are necessary in addition to vaccination to prevent infection. The “case‐case” case–control design provides a valuable method of calculating the effectiveness of this vaccine in travelers, given the availability of paratyphoid controls, a population with similar demographics and risk exposures.
Source: Journal of Travel Medicine - Category: Infectious Diseases Authors: Tags: ORIGINAL ARTICLE Source Type: research