Rasamsonia sp: An emerging infection amongst chronic granulomatous disease patients. A case of disseminated infection by a putatively novel Rasamsonia argillacea species complex involving the heart

Publication date: Available online 16 April 2019Source: Medical Mycology Case ReportsAuthor(s): Ahmed Babiker, Nupur Gupta, Connie F.C. Gibas, Nathan P. Wiederhold, Carmita Sanders, James Mele, Hongxin Fan, Alina Iovleva, Ghady Haidar, Carolyn FernandesAbstractChronic granulomatous disease (CGD) is a heterogeneous condition due to defects in NADPH oxidase characterized by granuloma formation and increased susceptibility to invasive infections, in particular moulds. The use of broad-spectrum, mould-active antifungal prophylaxis has improved mortality. However rare resistant moulds have emerged as important pathogens. Diagnosis of these rare fungi requires molecular techniques, and treatment data are limited. Herein, we present a case of with disseminated Rasamsonia infection involving the heart.

Source: Medical Mycology Case Reports - April 16, 2019 Category: Biology Source Type: research