The long and short of membrane curvature sensing by septins

Septin proteins form hetero-oligomers that associate with membranes of specific curvatures, but the mechanism is unknown. In this issue, Cannon et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201807211) identify a single amphipathic helix that is necessary and sufficient for membrane curvature sensing by septins.

http://jcb.rupress.org/cgi/content/short/218/4/1083?rss=1

Source: Journal of Cell Biology - March 31, 2019 Category: Cytology Authors: McMurray, M. A. Tags: Spotlight Source Type: research

More News: Biology | Cytology