Simultaneous LC/MS/MS quantification of eight apolipoproteins in normal and hypercholesterolemic mouse plasma [Methods]

In conclusion, we present a robust, quantitative LC/MS/MS method for the multiplexed analysis of eight apolipoproteins in mice. This assay can be applied to investigate the effects of genetic manipulation or dietary interventions on apolipoprotein levels in plasma and isolated lipoprotein fractions.

Source: The Journal of Lipid Research - March 31, 2019 Category: Lipidology Authors: Wagner, R., Dittrich, J., Thiery, J., Ceglarek, U., Burkhardt, R. Tags: Methods Source Type: research