Independent Validation of a Diagnostic Noninvasive 3-MicroRNA Ratio Model (uCaP) for Prostate Cancer in Cell-Free Urine [Cancer Diagnostics]

CONCLUSIONS:
We successfully validated a urine-based diagnostic 3-miRNA signature for PC (uCaP) in 3 independent patient cohorts from 2 countries. In the future, the simple and noninvasive uCaP test may be used to help more accurately select patients for prostate biopsy. Prospective clinical validation is warranted.

Source: Clinical Chemistry - March 27, 2019 Category: Chemistry Authors: Fredsoe, J., Rasmussen, A. K. I., Laursen, E. B., Cai, Y., Howard, K. A., Pedersen, B. G., Borre, M., Mouritzen, P., Orntoft, T., Sorensen, K. D. Tags: Cancer Diagnostics (since 2002) Source Type: research