Interleukin-35 promotes early endothelialization after stent implantation by regulating macrophage activation

Conclusions: We investigated the effect of IL-35 expression on early stent endothelialization in vivo and in vitro and identified a crucial role for IL-35 in inducing the activation of an anti-inflammatory M2-like macrophage phenotype. This study highlights a new therapeutic strategy for early stent endothelialization.

Source: Clinical Science - March 25, 2019 Category: Biomedical Science Authors: Liu, X., Zhang, R., Hou, J., Wu, J., Zhang, M., Fang, S., Wang, X., Huang, X., Tian, J., Li, H., Sun, Y., Yu, B. Tags: PublishAheadOfPrint Source Type: research