S8-Mediated Decarboxylative Cyclization of 2-Nitrophenols with Arylacetic Acid: Synthesis of Benzoxazoles

Publication date: Available online 21 March 2019Source: Journal of Saudi Chemical SocietyAuthor(s): Haifeng Gan, Dalong YangAbstractA concise, metal-free protocol has been established for the preparation of 2-arylbenzoxazoles from 2-nitrophenols and arylacetic acids via a sulfur-mediated redox decarboxylative cyclization reaction. The reactions proceeded in moderate to good yields, and gram-scale is suitable.Graphical abstract
Source: Journal of Saudi Chemical Society - Category: Chemistry Source Type: research