HBx induces the proliferation of hepatocellular carcinoma cells via AP1 overexpressed by ER stress

In conclusion, in HBV-infected hepatic cells or chronic hepatitis B patients, CREBH may induce proliferation of hepatic cells in cooperation with HBx, resulting in HCC.

Source: BJ Disease - November 27, 2014 Category: Biochemistry Authors: H Cho, S Kim, Y Kyaw, A Win, S Koo, H Kim, J Cheong Tags: BJ Disease Source Type: research