Population shrinkage of covariance (PoSCE) for better individual brain functional-connectivity estimation

Functional magnetic resonance imaging (fMRI) reflects neural activity in the brain through the blood-oxygen-level-dependent (BOLD) signal. Task-free or resting-state experiments (r-fMRI) are used to estimate brain functional connectivity between brain structures or regions. These pairwise interactions capture patterns that can be linked to the cognitive, psychiatric, or neurological status of individuals. With the advent of large cohort studies, functional connectivity has been used in neuroimaging population analyses to study cognitive differences between individuals (Smith et  al., 2015; Finn et al., 2015).
Source: Medical Image Analysis - Category: Radiology Authors: Source Type: research