Immunohistochemical evaluation of the epithelial–mesenchymal transition profile: Twist, E-cadherin, and vimentin in colorectal carcinoma

Conclusion Cytoplasmic Twist overexpression was negatively correlated with E-cadherin and positively correlated with vimentin in CRC and this confirms the EMT signature in CRC. Nucleocytoplasmic Twist expression was associated with poor prognostic factors in primary CRC, while cytoplasmic Twist expression was associated with poor prognostic factors in metastatic CRC.
Source: Egyptian Journal of Pathology - Category: Pathology Tags: ORIGINAL ARTICLES Source Type: research