Evolution of Epileptogenesis in response to head trauma and acute hemorrhagic conversion: A Stereoelectroencephalography (stereo-EEG) study

We present a unique case of a patient with medically refractory focal epilepsy undergoing presurgical stereoelectroencephalography (sEEG) evaluation who developed an acute post-traumatic intracranial hemorrhage during monitoring. Our case demonstrates the evolution of the electrographic changes at the time of the initial hemorrhage to the development of ictal activity. We conducted spectral analysis of the sEEG data to illustrate the transition from an interictal to ictal state. Initially, delta power increased in the region of acute hemorrhage, followed by a sustained regional reduction in frequency variability. Our findings provide further information on the development of epileptiform activity in acute hemorrhage.
Source: Epilepsy and Behavior Case Reports - Category: Neurology Source Type: research