Resistance is futile: Centering forces yield for asymmetric cell division

Asymmetric cell division relies on microtubule-based forces to asymmetrically position the mitotic apparatus. In this issue, Sallé et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201807102) use magnetic tweezers to induce asymmetric division in sea urchin zygotes, demonstrating that asymmetry could arise from a time-dependent weakening of centering forces.

http://jcb.rupress.org/cgi/content/short/218/3/727?rss=1

Source: Journal of Cell Biology - March 3, 2019 Category: Cytology Authors: Alper, J., Zanic, M. Tags: Spotlight Source Type: research

More News: Biology | Cytology