A Mendelian Randomization-Based Approach to Identify Early and Sensitive Diagnostic Biomarkers of Disease [Proteomics and Protein Markers]

CONCLUSIONS:
Our results suggest TFF3 is a valuable diagnostic marker for early CKD in dysglycemic populations and acts as a proof of concept for the application of this novel MR technique to identify diagnostic biomarkers for other chronic diseases.

ClinicalTrials.gov Identifier:
NCT00069784

Source: Clinical Chemistry - February 28, 2019 Category: Chemistry Authors: Mohammadi-Shemirani, P., Sjaarda, J., Gerstein, H. C., Treleaven, D. J., Walsh, M., Mann, J. F., McQueen, M. J., Hess, S., Pare, G. Tags: Proteomics and Protein Markers Source Type: research