Model-free tests for genetic linkage.

Model-free tests for genetic linkage.
Curr Protoc Hum Genet. 2012 Oct;Chapter 1:Unit1.8
Authors: Amos CI, Schnell A, Chen WV, Elston RC
Abstract
This unit covers statistical methods of linkage analysis that do not require the assumption of a detailed genetic model, as is required for standard lod score analysis. The unit has been updated to include the latest methods in sib-pair analysis, including updates to using the software program SIBPAL as well as the relative-pair analysis software applications GENEHUNTER, GENEHUNTER PLUS, and Merlin.
PMID: 23074068 [PubMed - indexed for MEDLINE]

Source: Current Protocols in Human Genetics - November 25, 2014 Category: Genetics & Stem Cells Tags: Curr Protoc Hum Genet Source Type: research