Weakly Supervised Mitosis Detection in Breast Histopathology Images using Concentric Loss

The most widely used invasive breast cancer grading system is the Nottingham Grading System (Elston and Ellis, 1991), which consists of three components: nuclear pleomorphism, tubule formation and mitotic count. Among them, mitotic count is the most important one since the propagation of cancer is mainly governed by cell division. Generally, the mitosis figures are marked manually by pathologists on the Hematoxylin and Eosin (H&E) stained slides. Counting mitosis manually is very time-consuming and subjective, thus it is extremely useful to develop an automatic detection method, which is capable of making this process more efficient and alleviating the bias of results from different pathologists.

Source: Medical Image Analysis - February 14, 2019 Category: Radiology Authors: Chao Li, Xinggang Wang, Wenyu Liu, Longin Jan Latecki, Bo Wang, Junzhou Huang Source Type: research