Mannitol versus hypertonic saline solution in neuroanaesthesia

Conclusion Data availability is limited because of small sample sizes, inconsistent methods and few prospective randomized comparative studies, although both agents are effective and have a reasonable risk profile for the treatment of cerebral oedema and IH. Currently, several trials show that HTS could be more effective in reducing ICP, with longer lasting effects. HTS maintains systemic and cerebral haemodynamics.
Source: Colombian Journal of Anesthesiology - Category: Anesthesiology Source Type: research