Experimental Obesity and Diabetes Reduce Male Fertility: Potential Involvement of Hypothalamic Kiss-1, Pituitary Nitric Oxide, and Serum Vaspin and Visfatin

In conclusion, obesity and diabetes, alone or combined, had a negative impact on male rat fertility. Moreover, obesity and diabetes combined had more harmful effects on male fertility when compared with obesity alone. Hypothalamic Kiss-1, pituitary NO, and serum vaspin and visfatin may play a role in the pathophysiology of male infertility-associated with obesity and diabetes.
Source: Pathophysiology - Category: Pathology Source Type: research