Dendritic cells mature to resist lamin degradation and herpes virus release

Herpes simplex viruses bud into the nuclear membrane of infected cells. Turan et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201801151) demonstrate that mature dendritic cells control the peripheral location of lysosomes, reducing autophagic degradation of lamins and inhibiting viral release.
Source: Journal of Cell Biology - Category: Cytology Authors: Tags: Virology, Trafficking Spotlight Source Type: research