The pharmacological management of agitated and aggressive behaviour: A systematic review and meta-analysis

ConclusionOlanzapine, haloperidol plus promethazine or droperidol are most effective and safe for use as rapid tranquilisation. Midazolam sedates most quickly. But due to increased saturation problems, midazolam is restricted to use within an emergency department of a general hospital.
Source: European Psychiatry - Category: Psychiatry Source Type: research