Enhanced behavioral responses to cold stimuli following CGRPalpha sensory neuron ablation are dependent on TRPM8

Conclusions: Our data indicate that the enhanced behavioral responses to cold stimuli in CGRPalpha sensory neuron-ablated mice are dependent on functional TRPM8, whereas the other sensory and thermoregulatory phenotypes caused by CGRPalpha sensory neuron ablation are independent of TRPM8.

http://www.molecularpain.com/content/10/1/69

Source: Molecular Pain - November 19, 2014 Category: Molecular Biology Authors: Eric McCoyMark Zylka Source Type: research