Lysophosphatidic acid and its receptors LPA1 and LPA3 mediate paclitaxel-induced neuropathic pain in mice

Conclusions: These results suggest that LPA1 and LPA3 receptors-mediated amplification of spinal LPA production is required for the development of paclitaxel-induced neuropathic pain.

http://www.molecularpain.com/content/10/1/71

Source: Molecular Pain - November 19, 2014 Category: Molecular Biology Authors: Hitoshi UchidaJun NagaiHiroshi Ueda Source Type: research