Digital pathology with Fourier ptychography

Fourier ptychographic microscopy (FPM) is a recently introduced method of acquiring high-resolution, wide field of view (FOV) giga-pixel histology images. The FPM procedure first acquires a sequence of low-resolution images of a sample under variable-angle illumination. It then combines these images using a novel phase retrieval algorithm to improve the employed microscope's resolution beyond its conventional limit. Here, we first describe how FPM's resolution improvement can enhance wide FOV histology imaging.

Source: Computerized Medical Imaging and Graphics - November 18, 2014 Category: Radiology Authors: Roarke Horstmeyer, Xiaoze Ou, Guoan Zheng, Phil Willems, Changhuei Yang Source Type: research