Evaluation of the Analytical Performance of the Modified Enterprise Point-of-Care Blood Gas and Electrolyte Analyzer in a Pediatric Hospital

AbstractArterial blood gas testing is an essential component that directs the evaluation of a patient’s general condition, especially in the emergent setting. We evaluated the analytical performance of the modified Enterprise point-of-care (EPOC) blood gas and electrolyte analyzer system with respect to precision and accuracy and compared our results with those obtained using the point-of-care i-STAT method and the criterion standard ABL 835 Radiometer blood gas analyzer in a pediatric hospital. Evaluation studies were performed as per the Clinical Laboratory Standards Institute guidelines and included intra-assay and interassay precision and accuracy, linearity, and concordance analyses with i-STAT and ABL 835 Radiometer. Intra-assay and interassay coefficient of variation for each analyte was calculated and was less than 6% for all analytes in the ranges tested including pH, Po2, Pco2, Na+, K+, Ca2+, glucose, lactate, and hematocrit, Cl−, and creatinine. All of the analytes were linear across the reportable range. For the methods comparison of EPOC system with the i-STAT method, using 40 samples, the correlation coefficients were r > 0.94 for all analytes with the exception of Ca2+ (r = 0.61).For the methods comparison of EPOC system with the criterion standard ABL 835 Radiometer on 40 samples, the correlation coefficients were higher than 0.97 for all analytes with the exception of hematocrit and hemoglobin (r = 0.8). Thus, in our pediatric hospital setting, the EPOC s...
Source: Point of Care: The Journal of Near-Patient Testing and Technology - Category: Pathology Tags: Original Articles Source Type: research