Development and Validation of Apolipoprotein AI-Associated Lipoprotein Proteome Panel for the Prediction of Cholesterol Efflux Capacity and Coronary Artery Disease [Proteomics and Protein Markers]

CONCLUSIONS:
Development of a proteomic pCE provides a reproducible high-throughput alternative to traditional cell-based CEC assays. The pCAD model improves stratification of case and control cohorts and, with further studies to establish clinical validity, presents a new opportunity for the assessment of cardiovascular health.

Source: Clinical Chemistry - January 28, 2019 Category: Chemistry Authors: Jin, Z., Collier, T. S., Dai, D. L. Y., Chen, V., Hollander, Z., Ng, R. T., McManus, B. M., Balshaw, R., Apostolidou, S., Penn, M. S., Bystrom, C. Tags: Proteomics and Protein Markers Source Type: research