Mesenchymal stem cells ameliorate diabetic glomerular fibrosis in vivo and in vitro by inhibiting TGF-{beta} signalling via secretion of bone morphogenetic protein 7

Conclusion:
MSCs ameliorated glomerular fibrosis in vivo and in vitro by inhibiting TGF-β/Smad signalling pathway via secretion of BMP7.

Source: Diabetes and Vascular Disease Research - June 16, 2014 Category: Endocrinology Authors: Lv, S., Liu, G., Sun, A., Wang, J., Cheng, J., Wang, W., Liu, X., Nie, H., Guan, G. Tags: Original Articles Source Type: research