Pfcrt 76T and pfmdr1 86Y allele frequency in Plasmodium falciparum isolates and use of self-medication in a rural area of Gabon

Conclusions
An increase of the frequency of P. falciparum wild type allele pfcrt 76K and pfmdr1 86N was observed within a short period after chloroquine withdrawal. The proportion of mutant genotypes is still high, mainly among patients using self-medication with antimalarial drugs.

Source: Transactions of the Royal Society of Tropical Medicine and Hygiene - October 9, 2014 Category: Tropical Medicine Authors: Mawili-Mboumba, D. P., Ndong Ngomo, J. M., Maboko, F., Guiyedi, V., Mourou Mbina, J. R., Kombila, M., Bouyou Akotet, M. K. Tags: ORIGINAL ARTICLES Source Type: research