Research Progress and Application of Ion Funnel Technique

Publication date: January 2019Source: Chinese Journal of Analytical Chemistry, Volume 47, Issue 1Author(s): Teng GUO, Zhen PENG, Hui ZHU, Li XU, Jun-Guo DONG, Zheng-Xu HUANG, Ping CHENG, Zhen ZHOUAbstractIon funnel is a new-style ion guider which can reduce spatial divergence and energy dispersity of the transmission ions by using radio frequency (RF) electric field to confine the ions radially and the direct current (DC) axial electric field to move the ions toward the exit, and thus it can greatly increase the ion transmission efficiency and improve the sensitivity of the mass spectrometry. Since ion funnel was invented in 1997, it has attracted a close attention of mass spectrometry scientists all over the world. Ion funnel has been used in various kinds of mass spectrometry, and built a bridge with high efficiency ion transmission between low vacuum ionization source and high vacuum mass analyzer. In this paper, the principle, technology development, and application progress of ion funnel are reviewed, and the future prospects are prospected.Graphical AbstractIon funnel is a new-style ion guide which uses RF electric field to confine the ions radially and the DC axial electric field to drive the ions toward the exit. It can effectively capture, focus and transmit ions under high pressure, and thus greatly improve the sensitivity of the mass spectrometry. In this paper, the principle, technology development and application progress of ion funnel are reviewed, and the futur...

Source: Chinese Journal of Analytical Chemistry - January 10, 2019 Category: Chemistry Source Type: research