IL-17R-EGFR axis links wound healing to tumorigenesis in Lrig1+ stem cells

This study demonstrates that IL-17A activates the IL-17R–EGFR axis in Lrig1+ stem cells linking wound healing to tumorigenesis.

Source: The Journal of Experimental Medicine - January 7, 2019 Category: Internal Medicine Authors: Chen, X., Cai, G., Liu, C., Zhao, J., Gu, C., Wu, L., Hamilton, T. A., Zhang, C.-j., Ko, J., Zhu, L., Qin, J., Vidimos, A., Koyfman, S., Gastman, B. R., Jensen, K. B., Li, X. Tags: Solid Tumors, Stem Cells & Regeneration, Tumor Immunology Articles Source Type: research