Modeling height for children born small for gestational age treated with growth hormone

The analysis of growth curves of children can be done on either the original scale or in standard deviation scores. The first approach is found in many statistical textbooks, while the second approach is common in endocrinology, for instance in the evaluation of the effect of growth hormone in children that are born small for gestational age that remain small later in childhood. We illustrate here that the second approach may involve more complex modeling and hence a worse model fit.

Source: Statistical Methods in Medical Research - July 15, 2014 Category: Statistics Authors: Willemsen, S. P., de Ridder, M., Eilers, P. H. C., Hokken-Koelega, A., Lesaffre, E. Tags: Articles Source Type: research