Animal models of regression/progression of kidney disease

Publication date: Available online 22 August 2014 Source:Drug Discovery Today: Disease Models Author(s): Beom Jin Lim , Hai-Chun Yang , Agnes B. Fogo Current medical therapies may delay chronic kidney disease (CKD) progression. However, increasing experimental evidence indicates remission or even regression can be achieved. To study mechanisms progression versus regression by different interventions, appropriate animal models and research design must be implemented. We review key information of selected models, including etiology, pathogenesis, procedure, time course and assessment of potential regression.
Source: Drug Discovery Today: Disease Models - Category: Drugs & Pharmacology Source Type: research