Expressions of Transforming Growth Factor & #946; < sub > 1 < /sub > Signaling Cytokines in Aortic Dissection
Objective: To demonstrate the underlying mechanisms of aortic dissection compared to
those of coronary artery disease in terms of the transforming growth
factor-beta (TGF- β) signaling pathway.Methods: Twenty consecutive aortic dissection patients and 20 consecutive coronary
artery disease patients undergoing a surgical treatment in this hospital
were enrolled into this study. The aortic tissues were sampled and the
TGF- β1 and its receptor TGF-β receptor I
(TβRI) were detected by Western blotting assay.Results: TGF- β1 and TβRI were positively expressed in the
aortic tissues in both groups by Western blotting assay. ...
Source: Brazilian Journal of Cardiovascular Surgery - Category: Cardiology Source Type: research
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