An introduction to the informatics of "next-generation" sequencing.

An introduction to the informatics of "next-generation" sequencing.
Curr Protoc Bioinformatics. 2011 Dec;Chapter 11:Unit 11.1.
Authors: Stein LD
Abstract
Next-generation sequencing (NGS) packs the sequencing throughput of a 2000's-era genome center into a single affordable machine. However, software developed for conventional sequencing technologies is often inadequate to deal with the nature of NGS technologies, which produce short, massively parallel reads. This unit surveys the software packages that are available for managing and analyzing NGS data.
PMID: 22161566 [PubMed - indexed for MEDLINE]

Source: Current Protocols in Bioinformatics - November 12, 2014 Category: Bioinformatics Tags: Curr Protoc Bioinformatics Source Type: research