New dammarane-type triterpenoid saponins from Panax notoginseng saponins

ConclusionThree new triterpenoid saponins (1-3) together with twenty-five known rare saponins (4-28) were isolated from PNS, except for the five main compounds (notoginsenoside R1 and ginsenoside Rg1, Rd, Re and Rb1). In addition, the HPLC fingerprint of PNS was established, and the peaks of the isolated compounds were marked. The study of chemical constituents and fingerprint were useful for the quality control of PNS. The study on antitumor activities showed that new compound 2 exhibited significant inhibitory activity against the tested cell lines.
Source: Journal of Ginseng Research - Category: Complementary Medicine Source Type: research