Polyphyly in 16S rRNA-based LVTree Versus Monophyly in Whole-genome-based CVTree

In this study, we reconstructed phylogenetic relationship for more than ten thousand prokaryote genomes by using the CVTree method, which is based on whole-genome information. And many such genera, which are polyphyletic in 16S rRNA-based trees, are well resolved as monophyletic clusters by CVTree. We believe that with genome sequencing of prokaryotes becoming a commonplace, genome-based phylogeny is doomed to play a definitive role in the construction of a natural and objective taxonomy.

Source: Genomics, Proteomics and Bioinformatics - December 12, 2018 Category: Bioinformatics Source Type: research