Profiling gene promoter occupancy of Sox2 in two phenotypically distinct breast cancer cell subsets using chromatin immunoprecipitation and genome-wide promoter microarrays

Conclusions:
In conclusion, our data supports the model that the Sox2 induces differential gene expression in the two distinct cell subsets in BC, and contributes to their phenotypic differences.

Source: Breast Cancer Research - November 8, 2014 Category: Cancer & Oncology Authors: Karen JungPeng WangNidhi GuptaKeshav GopalFang WuXiaoxia YeAbdulraheem AlshareefGilbert BigrasTodd McMullenBassam AbdulkarimRaymond Lai Source Type: research