Boolean AND and OR logic for cell signalling gateways: a communication perspective

In this study, the authors provide communication aspect of the signalling pathways that have two input Boolean logic AND/OR implemented at the rear effector protein. Communication is assumed to be taking place in extracellular and intracellular environment. The two environments are connected using a receptor protein acting as relay between a molecular source and effector protein. Each relay detects molecules from outside environment and stimulates the production of signals in the intracellular space. These signals/molecules further activate the effector protein which acts as a Boolean switch driven by AND/OR logic. Assuming Poisson reception at the relay as well as at the receiver, the authors provide probability of error of the AND and OR Boolean logic communication systems. Furthermore, reliability and some capacity bounds are deduced for the given Boolean communication system.
Source: IET Nanobiotechnology - Category: Nanotechnology Source Type: research