Dental pulp stem cells in chitosan/gelatin scaffolds for enhanced orofacial bone regeneration

The regeneration of alveolar bone defects to restore aesthetics and function in a predictable manner while offering a sustainable treatment outcome remains a major challenge still to be addressed despite recent advances in regenerative treatments. Alveolar bone defects may vary in nature; being associated with chronic inflammatory diseases, such as periodontitis or peri-implantitis, injuries, congenital disorders or resorption of the alveolar bone following tooth loss, all leading to noticeable deformity, impaired function and an overall compromised quality of life for patients; this latter being further aggravated by an increasingly ageing population [1].

Source: Dental Materials - December 6, 2018 Category: Materials Science Authors: Athina Bakopoulou, Αnthie Georgopoulou, Ioannis Grivas, Chryssa Bekiari, Oleg Prymak, Κateryna Loza, Matthias Epple, George C. Papadopoulos, Petros Koidis, Μaria Chatzinikolaidou Source Type: research