Optimization of a non‐viral transfection system to evaluate Cox‐2 controlled IL‐4 expression for osteoarthritis gene therapy in vitro

ConclusionWe hypothesize that this approach has significant potential to be translated into a useful anti‐inflammation therapy. Molecular tools such as the described therapeutic plasmid pave the way for a local‐controlled, self‐limiting gene therapy. This article is protected by copyright. All rights reserved.

Source: The Journal of Gene Medicine - September 1, 2014 Category: Genetics & Stem Cells Authors: Annemarie Lang, Johannes Neuhaus, Moritz Pfeiffenberger, Erik Schröder, Igor Ponomarev, Yvonne Weber, Timo Gaber, Michael F.G. Schmidt Tags: Research Article Source Type: research